Applications of boron clusters in nanoconstruction – present and future

Prof. Zbigniew Leśnikowski, (Poland)

Video was recorded during the 6th International research and practice Conference "Nanotechnolgy and Nanomaterials" (NANO-2018)

Modern chemistry with refined orthogonal conjugations and highly sensitive, high-resolution analytics in vitro and in vivo, facilitates development of advanced hybrid smart materials for technical and biomedical application. The discovery of polyhedral boranes, and later the synthesis of carboranes and their metal complexes, metallacarboranes in 1960s, created the foundation for new field of material and medicinal chemistry [1,2]. Boron clusters find application in many areas of material sciences including nanotechnology [3].

In nanoscience major use of boron clusters include surface modification, nanomachines and building blocs for nanoconstruction. The serach for molecular motors and actuators capable of delivering useful work to nanomachines is one of the objectives of nanotechnology. The adaptation of metalla-carborane structures to the design and synthesis of such rotor devices offers one of the possible formats [4]. Nanoporous materials such as metalorganic frameworks (MOFs) with tailorable pore volumes, high internal surface areas, and chemical diversity form an important emerging class of materials that are potentially useful in a wide range of applications. The unique icosahedral arrangement of the carborane-derived ligand allows for tuning properties of such structures [5]. Emerging boron cluster/DNA composites as building blocs for nanoconstruction offers another exciting application of boron clusters in nanotechnology [6].

 

Acknowledgements

Supported in part by the National Science Center, Poland, grant 2015/16/W/ST5/00413, contributions from the Statutory Fund of IMB PAS is also gratefully acknowledged.

 

References

[1] Grimes, RN. Carboranes, 3nd ed., Academic Press 2016.

[2] Leśnikowski, Z.J., Exp. Op. Drug Disc., 2016, 11, 569-578.

[3] Dash, B.P. Satapathy, R., Maguire, J.A., Hosmane, N.S.  New J. Chem.,2011,35, 1955.

[4] Hawthorne, M.F., Zink, J.I., Skelton,J.M., Bayer, M.J., Liu, C., Livshits, E., Baer, R. Neuhauser, D., Science, 2004, 303, 1849-1851.

[5] Mirkin, C.A., et al., Chem. Mater., 2013, doi.org/10.1021/cm4020942

[6] Janczak, S., Olejniczak, A., Balabańska, S., Chmielewski, M.K., Lupu, M., Viñas, C., Lesnikowski, Z.J. Chem. Eur. J. 2015, 21, 15118.